MOLECULAR TESTING

Molecular Testing

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  • EXPECTED TURNAROUND TIME 

    24 Hours 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN
    Nasopharyngeal Swab

    VOLUME
    3 mL (minimum volume- 1mL)

    CONTAINER
    The Bio Teke Viral Transport Device

    STORAGE INSTRUCTIONS 
    Refrigerated (2-8 °C)

    STABILITY REQUIREMENTS 
    7 days at 2-8 °C and 14 days at -70°C or lower. Avoid repeated freezing and thawing. 

    TEST DETAILS

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected

    STATEMENT ON MEDICAL NECESSITY 
    Sexually transmitted diseases (STDs) represent a significant public health concern due to their potential to cause serious health complications if left untreated. STDs can lead to a range of issues including infertility, chronic pain, and increased susceptibility to HIV. Early detection and management are crucial for effective treatment and to prevent transmission to others. All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES
    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a
    lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Alliance Laboratories Sexually Transmitted Diseases (STDs) Panel consist of 14 organisms and 4 antibiotic resistance targets manufactured with the fluidity to formulate custom panels. Alliance Laboratories encourages clients to contact their Alliance representative if the testing panel shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance Laboratories may bill specific carriers using codes other than what is shown.

  • EXPECTED TURNAROUND TIME 

    24 Hours 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN 
    Fecal swab or Fecal Specimen

    CONTAINER
    Fecal swab Collection, transport and preservation System

    STORAGE INSTRUCTIONS 
    Room temperature 24-48 hours; Refrigerated (2-8 °C) 48-72 hours.

    STABILITY REQUIREMENTS 
    7 days at 2-8 °C and 14 days at -70°C or lower. Avoid repeated freezing and thawing. 

    TEST DETAILS

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected

    STATEMENT OF MEDICAL NECESSITY 
    All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered, and the diagnosis should be documented in the provider’s medical record for the patient. Gastrointestinal panels are critical in diagnosing infectious and non-infectious conditions affecting the gastrointestinal tract. Accurate identification of pathogens and other abnormalities is essential for effective treatment, preventing complications, and managing symptoms. GI panels help in distinguishing between different causes of gastrointestinal illness, which can lead to appropriate and targeted therapeutic interventions. The gastrointestinal panel is a crucial diagnostic tool for identifying the causes of gastrointestinal symptoms and guiding appropriate treatment. By providing comprehensive information about potential pathogens and abnormalities, the panel supports targeted therapy, enhances patient care, and aids in the effective management of gastrointestinal conditions. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES
    Targets Included
    Adenovirus
    Astrovirus
    Campylobacter spp
    Clostridium difficile
    Cryptosporidium spp
    Dientamoeba fragilis
    Entamoeba histolytica
    Enteroaggregative E. coli
    Enterohemorrhagic E. coli
    Enteroinvasive E. coli (Shigella)
    Enteropathogenic E. coli
    Enterotoxigenic E. coli
    Escherichia coli (O157)
    Giardia lamblia
    Helicobacter pylori
    Norovirus G1
    Norovirus G2
    Plesiomonas Shigelloides
    Rotavirus
    Salmonella spp
    Sapovirus
    Shigella spp
    Vibrio cholerae
    Yersinia enterocolitica

    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Alliance Laboratories encourages clients to contact their Alliance representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance laboratories may bill specific carriers using codes other than what is shown.

  • EXPECTED TURNAROUND TIME 

    24-48 Hours 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN
    Clipped Nail

    VOLUME
    2 mL (minimum volume 1 mL)

    CONTAINER
    Sterile Nail collection tube

    STORAGE INSTRUCTIONS
    Room temp. 6 days, Refrigerated 6 days

    TEST DETAILS

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected

    ADDITIONAL INFORMATION
    Nail fungal infections (Nail Microbiota) are a group of infectious diseases where it is important to identify the pathology of nail deformation and determine a proper treatment plan. Fungi can infect almost any part of the body; however, these infections are most observed in the skin and nails, mainly on the foot. Nail fungal infections or onychomycosis are estimated to occur in over a billion people each year. It is the cause of roughly 50% of nail deformities and affects approximately 14-18% of adults. Anyone can acquire these infections, but the elderly and critically ill are often the most who commonly suffer. Real-time PCR OpenArray™ testing is important because conditions of psoriasis and malignant melanoma can mimic the appearance of fungal infections. A large proportion of Nail Microbiotas are asymptomatic or sub-clinical and hence go undiagnosed. Accurate and prompt identification of nail microbiota is the key to proper infection management for patients suffering from fungal and other pathogenic infections. Chronic nail infections often involve multiple organisms. The presence of these organisms is found extensively in the fungal group, which plays a substantial role in delayed healing, increased complications, and poor outcomes. Most skin fungal pathogens are colonized in both aerobic and anaerobic environments. Chronic nail fungal and other pathogen infections may cause substantial morbidity and are costly to treat. Several microorganisms are known to play a role in nail infections. For the successful treatment of nail microbiota, especially fungi, there is a need for precise and robust diagnostic methods. This test utilizes real-time PCR amplification to detect the presence of a microorganism in a nail sample by amplifying the genomic DNA of the organism. The TaqMan™ OpenArray™ nail microbiota assay is efficient and easy-to-use for the characterization of key nail microbial targets through real-time PCR. TaqMan™ OpenArray™ testing is fast and robust to contamination. This real-time PCR OpenArray™ test is ideal for the identification of these infections. Diagnostic methods that utilize fungal colonization/cultural identification can be time-consuming and may not completely illustrate all present pathogens due to the lack of sensitivity of the method created by the competition of multiple organisms in a single sample. TaqMan™ OpenArray™ testing (quantitative PCR, qPCR) has become an established method for rapid detection, quantification, and identification of microbial agents over the past decade. TaqMan™ OpenArray™ testing uses increased sensitivity and specificity to support the more accurate diagnosis of crucial infections, or lack thereof, to properly treat chronic fungal infections with faster turnaround times. Panel-based molecular testing not only help identify the presence of specific species but also profile Nail Microbiota pathogenic organisms, which would help understand its biological significance and may potentially provide guidance and reducing over-treatment. Microorganism‐specific TaqMan™ Assays offer a rapid and accurate approach to investigate and monitor Nail Microbiota microbiome composition and dynamics.

    REFERENCES
    1. “DNA Sequencing to Evaluate Nail Pathogens: An Investigation into Bacteria and Fungi”, NCBI, 2021 https://pubmed.ncbi.nlm.nih.gov/33872357/
    2. “Characterization of the nail microbiome in psoriatic and non-psoriatic patients with onychomycosis”, NCBI, 2022 https://pubmed.ncbi.nlm.nih.gov/34549836/

    STATEMENT OF MEDICAL NECESSITY 
    All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered, and the diagnosis should be documented in the provider’s medical record for the patient. Nail fungus infections, or onychomycosis, can cause significant discomfort, cosmetic concerns, and functional impairments. Accurate diagnosis is essential because the treatment varies depending on the type of fungus involved. A nail fungus panel provides precise identification of the fungal pathogen, which is necessary for effective and targeted treatment. A nail fungus panel is a vital diagnostic tool for accurately identifying fungal pathogens involved in nail infections. It allows for precise treatment decisions, improving the effectiveness of therapy and reducing the risk of persistent or recurrent infections. Early and accurate diagnosis facilitates better patient outcomes and effective management of nail fungal infections. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES
    Targets Included
    Acremonium strictum
    Alternaria_alternata
    Aspergillus fumigatus
    Aspergillus niger
    Aspergillus terreus
    Aspergillus versicolor
    Candida albicans
    Candida parapsilosis
    Curvularia lunata
    Epidermophyton floccosum
    Fusarium solani
    Geotrichum candidum
    Microsporum audouinii
    Microsporum canis
    Microsporum gypseum
    Microsporum nanum
    Pichia onychis
    Sarcoptes scabiei
    Scopulariopsis brevicaulis
    Neoscytalidium dimidiatum
    Trichophyton interdigitale, Trichophyton mentagrophytes
    Trichophyton rubrum
    Trichophyton soudanense
    Trichophyton interdigitale, Trichophyton mentagrophytes
    Trichophyton violaceum
    Trichosporon beigelii
    Trichosporon mucoides
    Zygosaccharomyces spp

    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Alliance Laboratories encourages clients to contact their Alliance representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance laboratories may bill specific carriers using codes other than what is shown.

  • EXPECTED TURNAROUND TIME 

    5 Days 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN
    Buccal Swab and Saliva

    VOLUME
    3 mL of saliva (minimum volume-1 mL of saliva)

    CONTAINER
    Dry Transport Container

    STORAGE INSTRUCTIONS
    Room Temp., Refrigerated (2-8 °C)

    STABILITY REQUIREMENT
    Room temp. 4 days, Refrigerated (2-8 °C) 7 days

    TEST DETAILS

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected 

    STATEMENT OF MEDICAL NECESSITY 
    All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered, and the diagnosis should be documented in the provider’s medical record for the patient. Pharmacogenomics is essential for tailoring medication therapy to individual genetic profiles, enhancing efficacy, and minimizing adverse drug reactions. By understanding how a patient’s genetic makeup influences their response to specific drugs, clinicians can make informed decisions about prescribing medications, leading to more effective and safer treatments. For patients who are beginning a new medication regimen or have a history of inadequate response or adverse effects to medications, to tailor therapy based on their genetic profile. In patients with chronic conditions requiring
    long-term medication management, where genetic factors may significantly impact drug metabolism and efficacy. The pharmacogenomics (PGX) panel is a crucial diagnostic tool for personalizing medication therapy, enhancing treatment efficacy, and reducing the risk of adverse drug reactions. By integrating genetic information into clinical decision-making, PGX panels support precision medicine and improve patient outcomes through individualized treatment plans. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES 
    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test
    combination/profile may be ordered separately as individual tests. Alliance Laboratories encourages clients to contact their Alliance representative if the testing configuration shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance laboratories may bill specific carriers using codes other than what is shown.

  • EXPECTED TURNAROUND TIME 

    24-48 Hours 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN
    Clean Catch Urine and Multi-test swab

    VOLUME
    3 mL of urine

    CONTAINER
    C&S Tube with preservative, Sterile Urine Transport Tube, Aptima Multi-test device

    COLLECTION INSTRUCTIONS
    Clean Catch

    STORAGE INSTRUCTIONS 
    Refrigerated (2-8 °C) for 7 days and at -70°C or lower for 14 days. Avoid repeated freezing and thawing. 

    STABILITY REQUIREMENTS 
    Refrigerated (2-8 °C) for 7 days and at -70°C or lower for 14 days. Avoid repeated freezing and thawing. 

    TEST DETAILS

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected

    STATEMENT OF MEDICAL NECESSITY 
    Sexually transmitted diseases (STDs) represent a significant public health concern due to their potential to cause serious health complications if left untreated. STDs can lead to a range of issues including infertility, chronic pain, and increased susceptibility to HIV. Early detection and management are crucial for effective treatment and to prevent transmission to others. All
    ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be
    documented. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES
    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Alliance Laboratories Sexually Transmitted Diseases (STDs) Panel consist of 14 organisms and 4 antibiotic resistance targets manufactured with the
    fluidity to formulate custom panels. Alliance Laboratories encourages clients to contact their Alliance representative if the testing panel shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance laboratories may bill specific carriers using codes other than what is shown.

  • EXPECTED TURNAROUND TIME 

    24-48 Hours 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN
    Urine

    VOLUME
    10 mL

    CONTAINER
    4ml aspirated volume to C&S tube

    COLLECTION INSTRUCTIONS
    Clean Catch 

    STORAGE INSTRUCTIONS 
    Room temperature for 24-48 hours, refrigerated (2-8°C) for 24-48 hours.

    STABILITY REQUIREMENTS
    Refrigerated (2-8°C) for 7 days

    TEST DETAILS 

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected

    STATEMENT OF MEDICAL NECESSITY
    All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered, and the diagnosis should be documented in the provider’s medical record for the patient. Urinary tract infections (UTIs) are common infections that can significantly impact an individual’s health and quality of life. They can lead to serious complications such as pyelonephritis, sepsis, and renal damage if
    not treated promptly. Early diagnosis and appropriate management are essential to alleviate symptoms, prevent progression, and reduce the risk of complications. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES
    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Alliance Laboratories encourages clients to contact their Alliance Laboratories representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance laboratories may bill specific carriers using codes other than what is shown.

  • EXPECTED TURNAROUND TIME 

    24-48 Hours 

    Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

    SPECIMEN REQUIREMENTS 

    SPECIMEN
    Wound Swab

    CONTAINER
    Liquid Amies Medium with Polyster Flock Swab

    STORAGE INSTRUCTIONS 
    Room temperature for 24-48 hours and Refrigerated (2-8 °C) for 24-48 hours

    STABILITY REQUIREMENTS 
    Refrigerated (2-8 °C) for 7 days and at -70°C or lower for 14 days

    TEST DETAILS

    METHODOLOGY
    PCR

    REFERENCE RANGE 
    Detected or Not Detected

    ADDITIONAL INFORMATION

    Each year millions of people suffer from nonhealing wounds, leading to unnecessary hospitalizations and lower-extremity amputations. The chronic wound epidemic is projected to grow annually because of an aging population with increased rates of obesity and diabetes. Patients with infected wounds can experience an abnormal healing process that can lead to longer-term care, additional medications, pain, stress, depression, hospitalization, function and mobility loss, and higher healthcare costs for healthcare organizations and patients alike. With molecular testing, not only can the type and percent of pathogens causing the infection to be visualized but, in many cases, the antimicrobial resistance can also be identified. With the power of molecular testing, the optimal medication therapy for the patient can be selected to improve treatment outcomes and reduce healthcare expenditure. Because efficiency and turnaround time are so important to physicians and their patients, the Applied Biosystems
    ThermoFisher panel uses real-time polymerase chain reaction (RT PCR). Nonhealing wounds are not so much a disease as a symptom. Patients with nonhealing wounds are likely to be older adults, non-ambulatory or paralyzed, unable to provide self-care, and/or having dementia. Their wounds may occur as a result of unique medical conditions (e.g., sickle cell anemia, vasculitis); in association with immunosuppression (e.g., steroid use), renal impairment (e.g., calciphylaxis), autoimmune diseases (e.g., systemic lupus erythematosus), dermatologic diseases (e.g., epidermolysis bullosa), and age-related debility or paralysis (which can lead to pressure ulcers); result from peripheral neuropathy (e.g., diabetes); and occur in patients with peripheral arterial and venous disease (e.g., arterial and venous ulcers). Accurate and prompt identification and determination of wound pathogens is key to proper wound management for patients suffering from pathogenic infection. Molecular diagnostics holds significant potential for improving the management of chronic wounds and ultimately enhancing patient outcomes.
    REFERENCES
    1. Nussbaum SR, Carter MJ, Fife CE, et al. An economic evaluation of the impact, cost, and Medicare policy implications of chronic nonhealing wounds. Value Health 2018;21(1):27-32.
    2. Rice J, Desai U, Ristovska L, et al. Economic outcomes among Medicare patients receiving bioengineered cellular technologies for treatment of diabetic foot ulcers. J Med Econ 2015;18(8):586-95.
    3. Santema TB, Poyck PPC, Ubbink DT. Systematic review and meta-analysis of skin substitutes in the treatment of diabetic foot ulcers: highlights of a Cochrane systematic review. Wound Repair Regen 2016;24(4):737-44.
    4. Landsman A, Rosines E, Houck A, et al. Characterization of a cryopreserved split- thickness human skin allograft—TheraSkin. Adv Skin Wound Care 2016;29:399-406.
    5. Landsman AS, Cook J, Cook E, et al. A retrospective clinical study of 188 consecutive patients to examine the effectiveness of a biologically active cryopreserved human skin allograft (TheraSkin) on the treatment of diabetic foot ulcers and venous leg ulcers. Foot Ankle Spec 2011;4:29-41.
    6. Adrian Barbul, MD; Helen Gelly, MD; and Arti Masturzo, MD, The Health Economic Impact of Living Cell Tissue Products in the Treatment of Chronic Wounds: A Retrospective Analysis of Medicare Claims Data

    STATEMENT OF MEDICAL NECESSITY
    All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Alliance Laboratories requires ICD-10 codes with each order for lab testing and both the tests ordered, and the diagnosis should be documented in the provider’s medical record for the patient. Wound infections can significantly impede healing, increase the risk of systemic infection, and lead to severe complications if not properly managed. A wound panel provides critical information about microbial etiology and antibiotic susceptibility, which is essential for tailoring effective treatment strategies. The use of a wound panel is a critical component of comprehensive wound management, allowing for precise diagnosis and effective treatment of infections. By identifying specific pathogens and their sensitivities, a wound panel supports targeted therapy, reduces the risk of complications, and promotes optimal healing. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

    PANELS AND PROFILES
    Test Includes Antibiotic Resistance Test Menu
    mecA
    mcr-1
    tetM
    tetS
    vanA
    vanB
    Sul1
    Bacteria Targets
    Acinetobacter baumannii
    Clostridium perfringens
    Clostridium tetanii
    Corynebacter amycolatum
    Corynebacter straitum
    Enterococcus faecalis
    Enterococcus faecium
    Escherichia coli
    Klebsiella pneumoniae
    Morganella morganii
    Proteus mirablis
    Pseudomonas aeruginosa
    Serratia marcescens
    Staphylococcus aureus
    Staphylococcus epidermidis
    Streptococcus agalactiae
    Streptococcus pneumoniae
    Candida albicans
    Candida glabrata
    Candida parapsilosis
    Candida tropicalis

    Alliance Laboratories offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Alliance Laboratories encourages clients to contact their Alliance representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

    CPT CODES
    CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Alliance laboratories may bill specific carriers using codes other than what is shown.

Precision Diagnostics for Enhanced Patient Care

Molecular testing is a cutting-edge diagnostic technique used to detect specific genetic material, such as DNA or RNA, within a sample. This form of testing allows for the precise identification of pathogens, genetic mutations, and other biomarkers, providing invaluable insights into a wide range of medical conditions. By analyzing molecular structures, our laboratory can offer highly accurate and timely diagnoses, which are essential for effective treatment planning and patient care.


Methodologies Used in Molecular Testing

Alliance Laboratories employ a variety of advanced methodologies to ensure precise and reliable molecular testing results:

Real-Time PCR (qPCR): This technique not only amplifies DNA but also quantifies it in real-time, providing both qualitative and quantitative data. Real-time PCR is especially useful for measuring viral loads and detecting specific mutations.

Reverse Transcription PCR (RT-PCR): Used primarily for detecting RNA viruses, RT-PCR converts RNA into DNA before amplification. This method is crucial for diagnosing infections caused by RNA viruses, such as COVID-19.

Next-Generation Sequencing (NGS): NGS allows for the comprehensive analysis of genetic sequences, identifying a wide range of genetic mutations and variations. This technique is particularly valuable for personalized medicine and complex disease diagnostics.

Multiplex PCR: This variation of PCR can simultaneously amplify multiple targets in a single reaction, making it highly efficient for detecting various pathogens in one test.

Discover Our Services

Our molecular testing services encompass a broad range of diagnostic tests designed to meet the diverse needs of our patients:

COVID/RSV/Flu A+B: Utilizing RT-PCR, we provide rapid and accurate testing for respiratory pathogens, including COVID-19, respiratory syncytial virus (RSV), and influenza A and B. Early detection and differentiation of these viruses are crucial for effective treatment and containment.

Gastro Pathogen Profile: Our gastro pathogen profile uses multiplex PCR to identify multiple gastrointestinal pathogens in a single test. This comprehensive approach ensures quick and accurate diagnosis of infections causing gastrointestinal symptoms.

Nail Fungal Infection: We employ PCR to detect fungal DNA in nail samples, providing a precise diagnosis of fungal infections. Early and accurate identification of the causative organism aids in selecting the most effective treatment.

Sexually Transmitted Infections (STIs) and Urinary Tract Infections (UTIs): Our molecular tests for STIs and UTIs use PCR to detect the genetic material of pathogens responsible for these infections. This allows for fast and reliable diagnosis, essential for prompt and appropriate treatment.

Wound Care (by PCR): We utilize PCR to identify bacterial and fungal pathogens in wound samples. Accurate detection of these pathogens is critical for effective wound management and treatment.

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