Alanine Transaminase (ALT)
0.5 mL Serum; Serum Separator Tube (red-grey marble)
Ambient – 7 Day(s), Refrigerated – 1 Month(s)
Note: Specimen will be discarded after 14 days of storage.
Avoid hemolysis. Avoid repeated freeze-thaw cycles.
Most commonly used and most prevalent in liver disease assessment. ALT = Alanine Aminotransferase. In comparison AST (aspartate amino transferase) is present to the sane extent in heart, skeletal muscle, and liver. AST and ALT increase rapidly during the onset of viral jaundice and remain elevated for 1-2 weeks. In toxic hepatitis, ALT and AST are elevated, but LD (lactate dehydrogenase) is elevated to an even greater extent as a result of hepatic cell necrosis. ALT and AST serum activities are elevated in myocardial infarction, renal infarction, progressive muscular dystrophy, and numerous diseases that only secondarily affect the liver, such as Gaucher’s Disease, Niemann-Pick disease, infectious mononucleosis, myelocytic leukemia, diabetic ketacidosis, and hyperthyroidism.
7.0 – 52.0 U/L